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#71Genetics & Molecular BiologyFront Page21 November 2025

Hidden Genetic Roots of Paediatric Brain Tumours Revealed

A comprehensive analysis of 830 young patients discovers that nearly a quarter carry inherited genetic mutations driving their disease. Surprisingly, the majority of these individuals had no prior clinical record of a genetic syndrome, highlighting an overlooked factor in tumour development.

By Corbett, Kaufman, McQuaid, Vaksman, Phul, Brown, Mason, Waszak, Zhang, Zhong, Blauel, Desai, Hausler, Naqvi, Daggett, Sickler, Cresswell-Clay, Sullivan, Chroni, Geng, Gonzalez, Zhu, Heath, Li, Storm, Resnick, Maxwell, Cole, Waanders, Bornhorst, MacFarland, Rokita, Diskin

#72Environmental ScienceFront Page16 March 2026

Mining decarbonisation: How climate bonds could fund clean extraction

A new preprint study suggests a financial framework to turn mining emissions into a lucrative asset for climate bond investors. By factoring avoided emissions into project valuations, emerging economies could fund the shift to renewable-powered extraction.

By Sentsho

#73Medicine & HealthFront Page17 March 2026

Inside the VIP Club: How Science is Beating Primary central nervous system lymphoma

Researchers have analysed two decades of data to find the best drug combinations for treating a rare brain cancer. By personalising heavy-hitting chemotherapy and follow-up treatments, long-term remission is becoming a reality.

By Hamoud, Samperio, Codreanu, Dasanu

#74Computer Science & AIFront Page15 November 2025

Scientists Pinpoint Key Gene Driving Chronic Pain After Stroke

Researchers have identified a single gene, Gja1, in star-shaped brain cells called astrocytes as a key driver of debilitating pain following a specific type of stroke. The study, conducted in mice, implicates a form of iron-dependent cell death called ferroptosis as a crucial mechanism, revealing a promising new target for future therapies.

By Xiao, Gao, Wei, Zhang, Ge, Wang, Huang, Ma

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