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#1Genetics & Molecular BiologyFront Page11 March 2026

Mosaic analysis expands beyond recombinase limits with a new genome-wide CRISPR kit

Researchers have developed a comprehensive genome-wide gRNA-marker kit for Drosophila, bypassing the need for traditional recombinase sequences in genetic studies. This tool expands the capability to study previously inaccessible genes and cell types using CRISPR/Cas9-induced somatic recombination.

By Shen, Yeung, Ditchfield, Korn, Clements, Chen, Wang, Huang, Sheen, Jarman, Han

#2Genetics & Molecular BiologyFront Page23 March 2026

Beyond DNA Sequencing: How AI and Digital Phenotyping Will Shape the Next Decade of Medicine

While modern genomics has successfully mapped our biological blueprints, making sense of that massive data remains a significant hurdle. A new review explores how next-generation phenomics merges genetic data with real-time digital tracking to predict health outcomes. This shift suggests a more personalised, systems-level approach to medicine within the next decade.

By Ranga, Malhotra, Singh, Pandey

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