
#1Genetics & Molecular BiologyFront Page11 March 2026
Mosaic analysis expands beyond recombinase limits with a new genome-wide CRISPR kit
Researchers have developed a comprehensive genome-wide gRNA-marker kit for Drosophila, bypassing the need for traditional recombinase sequences in genetic studies. This tool expands the capability to study previously inaccessible genes and cell types using CRISPR/Cas9-induced somatic recombination.
By Shen, Yeung, Ditchfield, Korn, Clements, Chen, Wang, Huang, Sheen, Jarman, Han