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When cancer cells adapt to survive therapies, their biological workarounds create distinct new dependencies. Researchers have mapped how these survival pathways can expose tumours to targeted follow-up treatments.
A review of 30 studies shows that resting-state fMRI scans taken within 28 days of severe brain injury are consistently linked to a patient's recovery up to a year later.
A comprehensive review reveals that atherosclerosis involves rogue muscle cells, immune memory, and gut microbes, explaining why lowering cholesterol alone leaves substantial disease behind.
Heart muscle can burn sugar by moving lactate straight into mitochondria through a backup transporter when its main fuel gate is missing.
A pioneering trial showed that viral delivery of gene-editing tools can restore muscle proteins in people with Duchenne muscular dystrophy. However, a fatal immune reaction in one patient reveals a dangerously narrow safety margin.
In a trial of 336 patients arriving 24 to 72 hours after an ischemic stroke, late stroke thrombectomy improved 90-day recovery but increased the risk of brain bleeds and death.
A review of medical studies shows that while gut health affects paediatric fatty liver disease, direct clinical proof for microbiome-based treatments in young people remains limited.
A study tracking 480 adults with severe asthma shows that standard breathing tests used to filter trial participants do not change how well biologic treatments reduce dangerous flare-ups.
A study of over 9,000 people suggests oestrogen helps gut bugs make a bile acid that could help shield female livers by managing cholesterol.
A massive analysis shows that the non-live shingles vaccine protects adults with chronic inflammatory illnesses without setting off sudden disease flare-ups.