Archived Intelligence
Researchers have engineered a highly stable catalyst by anchoring single palladium atoms within a porous silica framework. This design creates a specialised environment that prevents the metal from clumping or washing away, solving a major hurdle in water-based chemical synthesis.
Researchers have developed a deep-learning model to rapidly predict the global electrophilicity index, a key measure of chemical reactivity. This approach matches the accuracy of complex quantum calculations at a fraction of the cost, identifying novel compounds for self-healing polymers.
Researchers have successfully combined Large Language Models with large-scale human proteomics data to better identify damaging genetic variants. This refined approach outperforms existing deep learning tools, significantly improving the discovery of gene-trait associations in complex human biology.
Researchers have developed Deep-ELA, a hybrid framework that uses pre-trained transformers to analyse the 'fitness landscapes' of complex mathematical problems. By training on millions of random scenarios, this self-supervised model overcomes the limitations of previous methods, offering a robust way to understand both single- and multiobjective optimization challenges.
A recent study demonstrates that large language models, specifically GPT-4o, significantly outperform traditional algorithms in identifying immunosuppressed patients within intensive care units. By analysing unstructured clinical notes, the AI matched or exceeded the accuracy of older methods, showing robust potential for medical research.
Scientists are optimising solar energy harvesting by utilising the tunable nature of Covalent Organic Frameworks (COFs) and Porous Organic Polymers (POPs). By refining the molecular backbones and pores of these materials, researchers can significantly enhance charge transfer and device performance in next-generation solar cells.
A major analysis of over 2,500 patients confirms that drug-coated balloons are more effective than standard balloons at keeping dialysis access points open for the first year. While this advantage fades after two years, the procedure is shown to be just as safe as traditional methods.
New research identifies that the genetic risk for schizophrenia associated with the protein FOXP1 is not static but fluctuates significantly during brain development. Surprisingly, the strongest genetic effects appear during the stage corresponding to early childhood, rather than at birth or adulthood.
A study in southern Mexico City reveals that well-intentioned reforestation is transforming alpine grasslands into dense forests, inadvertently threatening the rare volcano rabbit. By utilising citizen science, researchers identified that while some rabbits are resilient, specialised species require specific grassland preservation.
New research reveals that microplastics in aquaculture, specifically PVC from floating balls, act as hotspots for antibiotic resistance genes. These plastics harbour significantly more mobile genetic elements and pathogenic bacteria than wood debris or the surrounding water, posing a heightened ecological risk.
Construction of offshore wind farms causes a temporary disruption to microscopic marine life, yet populations recover surprisingly quickly. However, the long-term presence of turbines alters the stability and connectivity of these ecosystems, likely due to predation from new marine life attracted to the structures.
A systematic review of 49 studies reveals that while researchers are actively using machine learning to predict diabetes complications, they have yet to adopt recent breakthroughs like generative AI. Although eye-related issues are the most studied focus, significant opportunities remain in analysing unstructured data such as medical images.
Researchers have successfully engineered a silicon metasurface that stabilises quantum light emission in MoSe2 monolayers at room temperature. By amplifying specific light interactions, this platform overcomes previous stability issues to create efficient, ultracompact light sources.
Scientists have successfully generated higher-order topological states at specific vacancies inside materials, rather than restricting them to the outer corners. These 'point states' carry a fractional charge and have been verified in both acoustic and photonic experiments, offering unprecedented control for future devices.
Researchers have identified a rare case where a patient’s immune cells spontaneously corrected a genetic defect, resolving a chronic Epstein-Barr virus infection. This natural phenomenon, known as somatic reversion, suggests that gene therapy could successfully treat similar immune deficiencies.
Researchers have successfully assembled a functional Pseudorabies virus genome using yeast-based recombination and CRISPR technology. This new platform overcomes the difficulties of editing complex viral DNA, paving the way for faster development of vaccines for the swine industry.
A comprehensive systematic review of studies up to January 2025 has identified crucial predictors for 30-day mortality in sepsis patients. While confirming severe risks like septic shock and liver disease, the analysis uncovered surprising evidence that diabetes and urinary tract infections may act as protective factors.
Deep brain stimulation treats Parkinson’s disease by shifting the brain from a state of broad, inefficient activity to one of focused motor dominance. This global rebalancing aids movement recovery but may involve trade-offs with non-motor brain functions.
Scientists have identified specific brain connections that predict impulsivity in teenagers. By scanning 95 adolescents, the study found that stronger links between the brain's salience network and the locus coeruleus correlate with more frequent errors and false alarms.
Researchers have engineered a magnetic catalyst that uses white LED light to efficiently convert biomass sugars into EMF, a high-energy biofuel additive. This sustainable process operates under mild conditions and allows the catalyst to be easily recovered and reused multiple times.
Researchers have discovered that low levels of thyroxine during pregnancy trigger an inflammatory response that disrupts foetal brain development in mice. This condition leads to structural deficits in the hippocampus, but restoring hormone levels can prevent the damage.
Using high-resolution MRI, researchers have mapped the complex connectivity of ocular dominance columns in the human primary visual cortex. The study reveals that connections are strongest between brain structures sharing the same eye preference, whilst also uncovering distinct patterns in peripheral and dorsal visual fields.
Researchers have identified that SREBF2, a key controller of cholesterol metabolism, acts as a significant driver of disease progression in acute myeloid leukaemia. High levels of this protein correlate with poor patient survival, marking it as a vital new tool for prognosis.
Following the severe 2024 mass bleaching event, coral reefs in southwest Madagascar's Mahafaly Seascape demonstrated unexpectedly high recovery rates. The study reveals that despite significant thermal stress, mortality remained low, suggesting these understudied ecosystems may serve as resilient sanctuaries against climate change.