The Missing Link in AI-Driven Diabetes Prediction
Source PublicationJournal of Diabetes Science and Technology
Primary AuthorsPescol, Bosoni, Ghilotti et al.

Managing diabetes requires constant vigilance to prevent serious complications affecting the eyes, heart, and nerves. To help navigate this biological complexity, scientists are turning to Artificial Intelligence (AI) to build predictive models. A recent systematic review analysed 49 studies to assess how effective these digital tools are at forecasting risks. The results highlight a fascinating concentration of effort: nearly 60% of the research focused specifically on eye-related complications, making vision loss the primary target for current predictive algorithms.
Technically, the landscape is dominated by standard Machine Learning techniques, which appeared in over half of the studies. However, a surprising gap emerged in the data. Despite the global buzz surrounding generative AI and 'foundation models'—the powerful systems capable of generalising across different tasks—not a single study in this review employed these cutting-edge technologies. Furthermore, only 10% of the research utilised unstructured data, such as raw medical signals or images, relying instead on structured tabular data.
When determining who is most at risk, the algorithms consistently pointed to two main factors: the patient's age and their levels of glycated haemoglobin (a measure of average blood sugar). While the current literature is extensive, the review suggests we are barely scratching the surface. The future of diabetes care likely lies in integrating these ignored AI advancements and learning to decipher the rich, unstructured data hidden in medical scans.