Archived Intelligence
Researchers have demonstrated that astrocytes actively protect brain connections from toxic amyloid beta by clearing excess glutamate. This early cellular defence mechanism delays structural damage in laboratory models, though the protective effect may fail during chronic exposure.
For decades, diagnosing schizophrenia has relied entirely on clinical observation rather than physical evidence. A new study analysing resting-state brain scans suggests that tracking how the brain routes and duplicates information could finally provide reliable, objective biological markers for the disorder.
Researchers have identified a specific gene, RAD23B, that declines significantly as the human hippocampus gets older. This discovery provides a new potential biomarker and therapeutic target for age-related cognitive decline.
Researchers have combined focused ultrasound stimulation with local field potential recordings to track brain activity at submillimetre and millisecond scales. This approach bypasses the traditional trade-offs between spatial and temporal precision seen in fMRI and EEG.
Researchers have mapped the functional organisation of the brain in individuals with autism, identifying a specific structural reduction in the left frontal lobe. This shift, paired with compensatory growth elsewhere, offers a biological explanation for the condition's diverse traits.
Researchers discovered that large language models are significantly better at pulling vital data from messy surgical notes than older algorithms. The AI can even use context clues to infer missing information, potentially saving hospitals hundreds of hours.
Researchers have linked lower motor cortex excitability in older adults to decreased brain network connectivity and lower cognitive scores. By monitoring the brain's baseline electrical activity, clinicians could soon detect early neurological vulnerabilities long before physical or mental symptoms emerge.
Prescribing the correct initial dose of epilepsy medication for children is notoriously difficult due to marked variations in how their bodies process the drug. A new machine learning model successfully predicts the optimal starting dose using basic patient data, offering a pathway to reduce toxic side effects and improve seizure management.
A recent comprehensive review evaluates the efficacy of targeting hormonal and metabolic pathways to manage chronic skin inflammation. While biologic drugs dominate recent headlines, this analysis suggests that combining endocrine therapies with lifestyle modifications offers a highly effective, multi-modal approach.
Developing a new medicine often takes over a decade and costs billions, leaving patients with rare diseases waiting in the dark. A comprehensive review suggests that artificial intelligence could accelerate finding new uses for existing medicines, halving the time and cost required to bring treatments to the clinic.
Splitting water to create green hydrogen has long been limited by the sluggish oxygen evolution reaction at the anode. A new comprehensive review outlines how perovskite materials offer a low-cost, highly tunable solution to this problem. By refining these compounds, scientists could accelerate the viability of clean hydrogen fuel.
Researchers have developed a deep learning model that accurately forecasts chlorophyll-a levels one day in advance, though its reliability drops sharply over a month. By applying explainable AI, the team identified exactly which environmental factors drive these forecasts across different timeframes.
Scientists have found that Mediterranean seagrass seeds come pre-packaged with a beneficial community of bacteria and fungi. This built-in microbial survival kit has the potential to help young plants establish themselves in harsh ocean environments.
Researchers have measured how airborne ash from Mediterranean fires alters ocean microbes. By introducing fine ash into controlled seawater tanks, the study shows a sudden shift in microbial diversity and abundance, providing experimental data to help understand downstream effects on ocean health.
Researchers have discovered that androgen signalling in early development stalls the maturation of brain cells, leaving infant boys highly vulnerable to a specific brain cancer. Blocking these hormones in laboratory models successfully halted the tumour's growth, suggesting a potential new treatment strategy.
Childhood immunisation rates have stalled, partly due to vaccine hesitancy, creating a bottleneck in public health. A new systematic review shows that teaching students directly about vaccines significantly improves their knowledge and may contribute to increased uptake, particularly for HPV.