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#461NeuroscienceFront Page6 February 2026

Reduced Gray Matter and the Psychological Readiness for Return to Sport

A cross-sectional study reveals that patients with ACL reconstruction exhibit significantly smaller gray matter volume in pain-processing brain regions compared to healthy controls. These structural differences correlate with lower confidence in returning to physical activity.

By Zhang, Xue, Yang, Wang, Lu, Wang, Hua

#462NeuroscienceFront Page1 December 2025

The Double Hit: How Pre-Birth Stress Amplifies Adult Memory Loss

Research reveals that exposure to stress in the womb can create a lasting vulnerability, exacerbating memory problems if the individual faces chronic stress in adulthood. This biological 'priming' appears to suppress genes essential for brain plasticity while elevating specific stress-response markers.

By Dogani, Askari, Vaez‐Mahdavi

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