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#1252NeuroscienceFront Page28 March 2026

Predicting Cognitive Impairments in Schizophrenia: A Cellular Bridge to Brain Function

Researchers have successfully linked individual cellular defects in lab-grown neurons to whole-brain structural and cognitive changes in patients. This multiscale approach offers a direct biological explanation for specific cognitive deficits.

By Raabe, Popovic, Vetter, Fischer, Hasanaj, Karslı, Schäfer, Almeida, Atella, Gagliardi, Boudriot, Yakimov, Trastulla, Jiang, Weyer, Roell, Moussiopoulou, Krčmář, Galinski, Papazova, Pogarell, Hasan, Schulte, Schmitt, Koutsouleris, Levina, Wagner, Rossner, Papiol, Falkai, Keeser, Ziller, CDP Working Group, Behrens, Boudriot, Chang, de Almeida, de Jonge, Dengl, Dürrwald, Falkai, Fischer, Gabellini, Gabriel, Galinski, Geyer, Hanken, Hasan, Hasanaj, Hisch, Ioannou, Ising, Jäger, Jiang, Kallweit, Karali, Karch, Karslı, Keeser, Kern, Klimas, Korman, Koutsouleris, Krcmar, Meisinger, Melcher, Mortazavi, Moussiopoulou, Neumeier, Padberg, Papazov, Papazova, Papiol, Pingen, Pogarell, Priglinger, Raabe, Roell, Rossner, Sämann, Schmitt, Schmölz, Schulte, Schulz, Schworm, Seeburger, Wagner, Wichert, Yakimov, Zill, Ziller

#1253Medicine & HealthFront Page16 November 2025

AI-Powered Chip Spots Ten Cancers From a Single Blood Test

Scientists have developed an AI-powered chip that can detect ten different types of cancer from a single blood serum test with remarkable accuracy. By analysing the unique molecular 'fingerprints' of tiny particles called exosomes, the system not only distinguishes cancerous from healthy samples but has also identified a promising universal marker for cancer.

By Zhang, Zhao, Zuo, Zhou, Hou, Wang, Shi, Yang, Liu, Sun, Ren, Ye, Liu, Li, Chen, Hao

#1254Neuroscience8 November 2025

Left Area PF: The Brain's 'Technical Hub' Supporting Human Ingenuity

Researchers suggest that grey matter volume in the left area PF, within the supramarginal gyrus, may predict individual differences in technical reasoning—the ability to infer and manipulate the causal structure of the physical world. These findings suggest this area may provide essential computational resources for technical cognition, offering insights into the neural basis of technological innovation and humanity's distinctive capacity for complex technologies.

By Federico, Ilardi, Marangolo, Bryche, Metaireau, Bluet, Lesourd, Rossetti, Osiurak

#1255NeuroscienceFront Page19 November 2025

Sound Waves Could Finally Reveal the Origins of Consciousness

Scientists are proposing a new roadmap for using transcranial focused ultrasound (tFUS) to map the neural origins of consciousness. Unlike older stimulation methods, tFUS offers precise, millimetre-scale access to deep brain structures without surgery, promising a major leap forward in understanding how we perceive reality.

By Freeman, Odegaard, Yoo, Michel

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