Archived Intelligence
Researchers engineered a shape-shifting nanoparticle that utilizes tumour acidity to trigger deep tissue penetration and immune activation. The system successfully co-delivers a macrophage inhibitor and a photosensitiser to overcome delivery barriers.
New research identifies how a specific gut bacterium influences neurobiology in distinct brain regions, offering a potential roadmap for treating neurodegenerative conditions. This precise host-microbe interaction suggests a future where living therapies replace blunt pharmacological tools.
Researchers have successfully demonstrated that living neurons can function as reconfigurable logic gates, switching between 'AND' and 'OR' functions based on spike timing. This study confirms that biological networks can perform logic-in-memory operations, providing a biological basis for future neuromorphic architectures.
This review evaluates the integration of carbon dots (CDs) into polymer matrices, asserting they enhance properties ranging from corrosion resistance to biocompatibility. It outlines synthesis methods and explores the mechanisms by which these zero-dimensional nanomaterials purportedly improve coating performance.
Researchers have sequenced the genomes of lenoks across China, revealing deep genetic fractures within the genus. The study identifies hidden cryptic species and exposes a complex history of hybridization, challenging how we classify these freshwater salmonids.
A decade of randomised trials confirms that early medical intervention for PDA in preterm infants fails to improve outcomes and increases mortality risk. Transcatheter options lack safety data. The data mandates an immediate shift to conservative, expectant management.
Researchers have developed a multi-stage deep learning framework to identify specific calcification patterns in paranasal sinus CT scans. This automated approach successfully differentiates aggressive fungal infections from standard chronic sinusitis.
Researchers have engineered a bifunctional catalyst using components derived directly from plastic waste to drive hydrogen production and electricity generation. This method integrates PET waste upcycling into a closed-loop energy system, bypassing the high costs and instability of traditional electrocatalysts.
Researchers have developed PRIQA, a specialised AI model that evaluates the clarity of microscopy images without needing a 'perfect' original for comparison. By training on human feedback, the system filters out low-quality data to improve the accuracy of automated parasite diagnoses.
Scientists have identified a novel genetic mutation in a rare bladder cancer, revealing how the loss of a key chromatin regulator causes cells to lose their identity and grow aggressively. The study highlights how this primary deficiency works alongside other genetic faults to drive the disease.
By recording directly from the human brain using over 5,000 electrode channels, researchers have mapped how we perceive objects. They discovered that an object's 'memorability' is processed separately from its visual look or meaning, suggesting a dedicated neural mechanism for deciding what is worth keeping.
Researchers have refined a method for extracting seabed samples without destroying their internal structure. By using detachable transparent tubes, the technique preserves the vertical zonation of marine life for lab study. It offers a clearer view of how organisms like clams interact with their layered environments.
Researchers investigated a blood donor whose physical blood type contradicted their genetic blueprint. By digging into the molecular machinery, they discovered a rare mutation that disrupts how cellular instructions are edited.