Archived Intelligence
Antimicrobial resistance is a growing global threat requiring advanced surveillance strategies. A new review highlights how artificial intelligence, ranging from deep learning to large language models, is revolutionising the detection of resistance proteins and the design of novel inhibitors to block them.
Cyproterone acetate is a common drug for treating hirsutism, a condition causing excessive hair growth in women. A major review finds that while effective, it generally performs similarly to alternative medications like spironolactone, though weak evidence from small studies limits definitive conclusions on safety and superiority.
Standard CRISPR/Cas9 editing is limited by its preference for specific DNA markers, leaving parts of the yeast genome inaccessible. A new study introduces an optimised CRISPR/Cas12a system that targets thymine-rich areas, allowing scientists to edit previously unreachable genetic sequences with high precision.
Scientists have engineered a robust catalyst that converts carbon dioxide into valuable chemicals at ambient pressure. By trapping palladium nanoparticles within a nitrogen-rich scaffold, the system prevents degradation and achieves near-perfect selectivity.
Researchers have developed ResTab Net, a new AI system that combines tissue images and protein data to diagnose breast cancer with 98.56% accuracy. Unlike traditional 'black box' models, this system uses explainable AI techniques to show clinicians exactly how it reaches its diagnostic conclusions.
Scientists have upgraded lithography-based 3D printing by replacing smelly, unstable thiols with readily available alcohols. Using light-activated catalysts, this 'oxa-Michael' reaction creates tough, uniform polymer networks ideal for high-temperature manufacturing.
Scientists are unlocking the secrets of 'inherently chiral macrocycles', unique ring-shaped molecules that lose their handedness if broken. Previously too difficult to synthesise, new methods are finally allowing researchers to exploit their potential for advanced materials and catalysis.
Researchers have developed a sophisticated modelling framework to simulate how repetitive magnetic stimulation physically alters brain connections. By replicating real-world experiments, this tool predicts how specific frequencies and locations strengthen synapses, aiding the design of better therapeutic protocols.
Scientists have engineered a unique three-layer crystal structure that creates a 'bichromatic' moiré superlattice. This material hosts exotic particles known as quadrupolar trions and offers precise control over quantum states via electric fields.
New satellite data reveals that the Arctic's ability to bury carbon, known as the biological pump, is undergoing a dramatic shift. While melting ice initially boosted this process, efficiency has recently plateaued and is projected to weaken further in a nearly ice-free future.
Researchers have engineered a highly efficient method to dismantle stubborn polyurethane plastics using zinc oxide and tert-butyl alcohol. This technique achieves over 99% depolymerisation, allowing the recovered chemical building blocks to be directly reused to create new materials.
CAR-T therapy has revolutionised blood cancer treatment but falters against solid masses due to hostile microenvironments. Scientists are now deploying CRISPR/Cas9 gene editing to reprogramme these cells, equipping them to infiltrate and destroy resilient tumours.
Researchers have overcome a critical durability flaw in inverted perovskite solar cells by designing a new polymeric hole transport layer. By improving uniformity and conductivity, this new material ensures high efficiency while preventing the device from breaking down under electrical stress.
Scientists have overcome a major barrier in optical computing, enabling light-based chips to run deep learning models with hundreds of layers rather than just ten. By eliminating specific signal redundancies that cause errors to pile up, the new 'SLiM' chip paves the way for energy-efficient hardware capable of running Large Language Models.
Scientists have developed a catalyst that physically evolves during operation to produce hydrogen more efficiently than commercial platinum. By leveraging the electronic structure of a barium-ruthenium oxide, they triggered the release of active ruthenium onto the material's surface, creating a highly potent system for water electrolysis.
Researchers have overcome a major noise hurdle in quantum photonics by successfully implementing resonant excitation in nanowire quantum dots. By using a 'mode-matching' technique to filter out blinding laser scatter, they achieved cleaner, coherent control of single photons, paving the way for scalable quantum devices.
Marine bacteria are essential for regulating global biogeochemical cycles, yet they face compounding threats from industrialisation and pollution. A new review highlights how the combination of climatic stressors and human contaminants, such as microplastics, impacts these vital organisms and their resilience.
Researchers have successfully used low-frequency ultrasonic waves to stimulate nerves in the arm without making physical contact, triggering a relaxation response in the body. This non-invasive technique specifically activates the parasympathetic nervous system, offering a potential drug-free future for treating conditions like anxiety and cardiac imbalance.
Researchers have achieved the first direct measurement of Hall voltage and resistance within a neutral-atom-based quantum simulator. This breakthrough bridges the gap between theoretical quantum simulations and practical solid-state physics, offering a new tool to study strongly correlated systems.
Robotic exoskeletons offer a promising new approach to cancer recovery, helping patients regain strength and combat fatigue through personalised, motion-assistive technology. While they integrate well with AI and digital therapeutics, high costs and a lack of large-scale trials currently limit their widespread adoption.
Researchers have introduced G4mer, a sophisticated RNA language model designed to identify complex structural elements called G-quadruplexes. This tool outperforms existing methods in predicting how genetic variations can alter these structures, revealing crucial links to breast cancer in often-overlooked genetic regions.
Repeated head injuries trigger a harmful overreaction from the brain's complement system, leading to cognitive decline. New research in mice reveals that inhibiting this immune pathway after trauma can prevent lasting brain damage and preserve memory.
Researchers have found that activating specific hypothalamic Q neurons triggers a hibernation-like state that aids recovery from traumatic brain injury in mice. This internal cooling mechanism significantly reduces harmful neuroinflammation and improves motor function without the risks associated with external cooling methods.
Researchers propose that microtubules, the structural scaffolds within cells, may function as scalable quantum computers operating at room temperature. By shielding fragile quantum states within their hollow interiors, these biological structures could enable dissipation-free energy transfer and complex information processing.