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Results for "Genetics & Molecular Biology"
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#852Computer Science & AIFront Page26 November 2025
New AI Model 'GPS-DTI' Navigates Uncharted Territory in Drug Discovery
Researchers have developed GPS-DTI, a deep learning framework that significantly improves the prediction of drug-target interactions. By modelling both local and global molecular features, the system offers robust generalisation for unseen drugs and specifically targets effective treatments, including for COVID-19.
By Xiong, Luo, Xia, Zou, Wei, Zhang, Wang, Wei, Cui
#853Genetics & Molecular BiologyFront Page21 November 2025
Watching Cas9 Edit DNA: Nanopores Track Enzymes in Real Time
Scientists have adapted high-resolution nanopore technology to detect exactly where the Cas9 enzyme binds to and cuts DNA strands. By analysing electrical signals as the complex passes through a sensor, this method allows for real-time monitoring of biochemical reactions on single molecules.
By Nagpure, Suresh, Shet, Soni
#854Genetics & Molecular BiologyFront Page13 February 2026
Missing Blueprints: The Genetics of Non-syndromic Hypodontia
Researchers sequenced the DNA of Jordanian patients to understand why some teeth fail to develop. While they identified specific genetic variants, the results suggest these may be harmless quirks rather than the direct cause of the condition.
By Areej Quran, Ahmed Maslat, Saied Jaradat, Eman Hammouri, Abeer Quran
#855Computer Science & AIFront Page14 November 2025
Gene Editing Turns Pest Pupae White for Smarter Farming
Scientists are using CRISPR gene editing to create a visible marker in major agricultural pests. By knocking out a specific gene, they produced fruit flies with white pupae, a trait that could revolutionise pest control by allowing for the easy separation of males for sterilisation programmes.
By Ioannidou, Gregoriou, Schetelig, Drosopoulou, Mathiopoulos, Bourtzis
#856Medicine & HealthFront Page15 November 2025
The Brain's Double-Edged Guardian: Meet the REST Protein
A crucial protein known as REST masterfully directs gene activity, shaping the developing brain and protecting it during normal ageing. However, when this powerful regulator falters, it becomes implicated in serious neurodegenerative diseases, making it a major focus for new therapeutic strategies.
By Eva, Shenoy, Gupta, Palanivel, Salkar, Nasab, Chitranshi, Mirzaei, You, Graham, Basavarajappa, Gupta