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#841Genetics & Molecular BiologyFront Page7 March 2026

The Ghost in the Bloodstream: Hunting for Cell-free RNA to Catch Cancer Early

Researchers measured genetic fragments in blood plasma to see if they could reliably identify cancer. They found that while these fragments vary wildly between individuals, simply counting the total number of highly abnormal genes can distinguish cancer patients from healthy donors.

By Morlion, Decruyenaere, Schoofs, Anckaert, Johns Ramirez, Nuytens, Vanden Eynde, Verniers, Everaert, Brusselle, Callens, Haerynck, Hemelsoet, Hoste, Lambert, Lumen, Offner, Paemeleire, Smith, Van den Eynde, Van Dorpe, Vanhaecke, Van Vlierberghe, Mariman, Thas, Vandesompele, Mestdagh

#842Environmental ScienceFront Page11 November 2025

New Glider Species Face Conservation Gaps Due to Research Bias

Recent taxonomic revisions have reclassified the greater glider into three distinct species, but a systematic review reveals a significant research bias towards only one. This uneven distribution of ecological knowledge threatens effective, species-specific conservation for the newly recognized central and northern gliders, demanding targeted research.

By Emerson, Kostaglou, Ashman, Cripps, Durkin, Eyre, Gracanin, Lindenmayer, Lo Cascio, Marsh, Mason, Miritis, Nelson, Wagner, Youngentob, Ritchie

#843Computer Science & AIFront Page1 December 2025

AI Cartographers: Mapping Complex Mathematical Landscapes

Researchers have developed Deep-ELA, a hybrid framework that uses pre-trained transformers to analyse the 'fitness landscapes' of complex mathematical problems. By training on millions of random scenarios, this self-supervised model overcomes the limitations of previous methods, offering a robust way to understand both single- and multiobjective optimization challenges.

By Seiler, Kerschke, Trautmann

#844Genetics & Molecular BiologyFront Page24 November 2025

CRISPR Upgrades Immune Cells to Breach Solid Tumours

CAR-T therapy has revolutionised blood cancer treatment but falters against solid masses due to hostile microenvironments. Scientists are now deploying CRISPR/Cas9 gene editing to reprogramme these cells, equipping them to infiltrate and destroy resilient tumours.

By Khodabandehloo, Rayati, Ahmadi, Naghdibadi, Moradi, Ahmadbeigi

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