
#821Genetics & Molecular BiologyFront Page22 January 2026
The Genome’s Dark Library: How DHX58 Complicates Gastric Cancer Immunotherapy
Researchers have identified DHX58 as a 'hub gene' that is stripped of its chemical constraints in stomach tumours. This overexpression, driven by the loss of methylation, appears to help the cancer evade the immune system.
By Li, Zhang, Wen, Wang, Zhang, Wang, Li, Kang, Gao, Yu, Du