Results for "Genetics & Molecular Biology"

Chasing Phantom Mutations: The Science Refining Precision Oncology

Researchers have developed a method to filter out false-positive genetic mutations in ovarian cancer cells, which often mislead targeted treatments. By combining DNA and RNA analysis, this study identified true vulnerabilities in tumours, potentially explaining why some targeted therapies fail.

By Muranen, Hainari, Afenteva, Senkowski, Oikkonen, Dreo, Driva, Holmström, Isoviita, Lahtinen, Lavikka, Li, Lovino, Maarala, Marchi, Miccolis, Micoli, Najm, Ostwaldt, Rodriguez-Mier, Söderlund, Hietanen, Virtanen, Saez-Rodriguez, Ficarra, Schwikowski, Alanne, Wennerberg, Hautaniemi, Hynninen