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#451Genetics & Molecular BiologyFront Page17 November 2025

Epigenetic Clues Uncover the Roots of Unexplained Male Infertility

Researchers have identified distinct molecular signatures in men suffering from idiopathic nonobstructive azoospermia (iNOA), a condition where sperm is absent without a clear cause. By analysing key epigenetic regulators, the study reveals that specific gene expression patterns can differentiate this condition from physical obstructions, offering hope for better diagnosis.

By Firouzabadi, Harimi, Heydari, Demehri, Mirghanizadeh Bafghi, Fesahat

#452Medicine & HealthFront Page14 November 2025

Scientists Forge New Metric to Quantify Plastic's Harm to Marine Life

Researchers have developed a 'global effect factor', a new universal metric to precisely quantify the harm plastic ingestion causes to marine mammals, seabirds, and sea turtles. This breakthrough provides a standardised way to include the physical impacts of plastic in formal Life Cycle Assessments, allowing it to be weighed against other environmental threats.

By Marhoon A, Murphy EL, Høiberg MA, Borgelt J, Dorber M, Verones F.

#453Environmental ScienceFront Page20 November 2025

Microplastics Stunt Sea Urchin Growth, Yet Recovery Remains Possible

New research reveals that polystyrene fragments from disposable plates cause severe developmental malformations in sea urchin larvae by disrupting critical gene networks. However, the study notably finds that these toxic effects are reversible, with embryos showing an ability to recover once the plastic contamination is removed.

By Amato, Gioia, Liotta, Cocca, Caramiello, Manfra, Libralato, Esposito, Zupo, Costantini

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