
Tandem DNA Repeats: Somatic Instability and Organ Failure Risk
Analysis of over 900,000 genomes reveals that repetitive DNA sequences expand significantly with age, driven by inherited genetic modifiers. These somatic mutations are strongly linked to severe kidney and liver diseases, challenging the assumption that our genome remains static throughout life.
By Hujoel, Handsaker, Tang, Kamitaki, Mukamel, Rubinacci, Palamara, McCarroll, Loh

