
#281NeuroscienceFront Page14 November 2025
Mapping the Brain's Shifting States in Alzheimer's Disease
New research reveals how the brain's dynamic connectivity patterns break down across the Alzheimer's spectrum. Early stages are marked by difficulty switching between neural states, while later stages see the brain becoming 'stuck' in dysfunctional patterns linked to specific genetic imbalances.
By Shi, Li, Ci, Yan, Tian, Zheng, Zhu, Qin