Global Intelligence Database
A massive meta-analysis reveals that taking antibiotics or proton pump inhibitors alongside immune checkpoint inhibitors can significantly reduce cancer survival rates. Conversely, probiotics appear to boost the effectiveness of these life-saving treatments by optimising the gut microbiome.
By Xu, Song, Fu, Zhou, Zhang, Shi
A study in middle-aged mice suggests the hormone melatonin can protect the brain and promote its ability to reorganise after a severe stroke. Mice treated with melatonin before an induced stroke showed significantly less brain damage, better behavioural recovery, and enhanced growth of neural connections compared to untreated mice.
By Chen, Tai, Huang, Tsao, Chen, Hsu, Lee, Lee
A new study in mice reveals a surprising paradox in the brain's stress-response system. Female brains possess a larger neural circuit for the chemical signal noradrenaline, yet its functional effect on the prefrontal cortex is more targeted and restricted compared to the broad-ranging impact seen in males, challenging long-held assumptions from male-only research.
By Scroger, Athanason, Paperny, Liss, Vo, Muneeb, Siddiqi, Batchelder, Shahbaz, Chan, Deak, Karkhanis, Varodayan