
#221Genetics & Molecular BiologyFront Page15 April 2026
Redundant immune pathways explain the high efficacy of mRNA-LNP vaccines
New research reveals that mRNA-LNP vaccines bypass traditional immune bottlenecks by utilising multiple dendritic cell types. This redundancy, driven by a process called cross-dressing, ensures robust T cell activation even in complex environments.
By Jo, Li, Thakur, Telfer, Sultan, Ohara, He, Nam, Chen, Ou, Draghi, Valiante, Schreiber, Randolph, Saligrama, Murphy, Gillanders, Murphy