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#2151Environmental ScienceFront Page25 November 2025

Madagascar’s Hidden Reefs Emerge as Vital Climate Refuges

Following the severe 2024 mass bleaching event, coral reefs in southwest Madagascar's Mahafaly Seascape demonstrated unexpectedly high recovery rates. The study reveals that despite significant thermal stress, mortality remained low, suggesting these understudied ecosystems may serve as resilient sanctuaries against climate change.

By Randrianarivo, Rakotomanga, Razafindramasy, Ravelojaona, Ranaivoson, Rakotomalala, Ratsimbazafy

#2152Medicine & HealthFront Page14 November 2025

Brain's Blueprint for Parkinson's Damage Revealed

A landmark study reveals that brain atrophy in Parkinson's disease follows a dual-front attack. The damage spreads through the brain's interconnected pathways, like a contagion on a transport network, while certain regions are inherently more vulnerable due to their genetic makeup.

By Vo, Tremblay, Rahayel, Al-Bachari, Berendse, Bright, Cendes, d'Angremont, Dalrymple-Alford, Debove, Dirkx, Druzgal, Garraux, Helmich, Hu, Jahanshad, Johansson, Klein, Laansma, McMillan, Melzer, Misic, Mosley, Owens-Walton, Parkes, Pellicano, Piras, Poston, Rango, Rummel, Schwingenschuh, Suette, Thompson, Tosun, Tsai, van Balkom, van den Heuvel, van der Werf, van Heese, Vriend, Wang, Wiest, Yasuda, Dagher

#2153Medicine & HealthFront Page15 November 2025

The Brain's Double-Edged Guardian: Meet the REST Protein

A crucial protein known as REST masterfully directs gene activity, shaping the developing brain and protecting it during normal ageing. However, when this powerful regulator falters, it becomes implicated in serious neurodegenerative diseases, making it a major focus for new therapeutic strategies.

By Eva, Shenoy, Gupta, Palanivel, Salkar, Nasab, Chitranshi, Mirzaei, You, Graham, Basavarajappa, Gupta

#2154NeuroscienceFront Page26 November 2025

Thyroid Imbalance During Pregnancy Sparks Brain Inflammation in Offspring

Researchers have discovered that low levels of thyroxine during pregnancy trigger an inflammatory response that disrupts foetal brain development in mice. This condition leads to structural deficits in the hippocampus, but restoring hormone levels can prevent the damage.

By González-Madrid, Rangel-Ramírez, Opazo, Espinoza, Elgueta, Cancino, Mery, Ardiles, Duarte, Soto, Carreño, Simon, Bueno, González, Kalergis, Riedel

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