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#2101Computer Science & AIFront Page13 November 2025

A Single Atom's Journey Defines a Nanocatalyst's Power

Scientists have unravelled why two copper nanoclusters, despite having almost identical surface defects, show strikingly different abilities to catalyse chemical reactions. The secret lies in a subtle atomic dance: in the effective cluster, a hydride atom moves to the defect site to activate it, while in the ineffective one, a copper atom's migration renders the defect useless.

By Ge, Chen, Deng, Fang, Pan, Shan, Gu, Sun, Zheng, Teo, Sun

#2102Medicine & HealthFront Page15 November 2025

Rusting the Brain: How Iron Overload May Trigger Anxiety

A study in rats reveals that excess iron in the body can accumulate in the brain, leading to increased anxiety-like behaviours. This overload triggers oxidative stress, a form of cellular damage, particularly in brain regions critical for regulating fear and anxiety.

By Maaroufi, Moulahi, Khadhraoui, Save, Sebai

#2103Medicine & HealthFront Page12 November 2025

Brain Connectivity Reveals Two Distinct Flavours of Depression

Major depression isn't a single condition, according to a new study of brain activity. Researchers have identified two distinct, reproducible subtypes based on brain connectivity: one with weaker-than-normal connections and another with stronger ones, each linked to different genetic and neurochemical profiles.

By Li, Li, Long, Chen, Wang, Yang, DelBello, McNamara, Li, Gong

#2104Computer Science & AIFront Page13 November 2025

Loyal Seals: Foraging Habits Persist Despite Decades of Ocean Change

Despite dramatic environmental reorganisation in their marine ecosystems, grey seals show remarkable long-term loyalty to their general home territories. While their favoured 'core' spots may shift year-to-year, their crucial foraging grounds remain strikingly consistent over time.

By Nowak, Bowen, Lidgard, den Heyer

#2105Medicine & HealthFront Page21 November 2025

Cleaning the Blood: The Complex Puzzle of Treating Sepsis

Sepsis triggers a dangerous immune response, but filtering the blood to fix it has yielded inconclusive results. Current broad-spectrum techniques risk removing beneficial molecules alongside harmful ones, highlighting a critical need for precision medicine.

By David, Rimmelé, Joannidis, Girardis, Pickkers, Nielsen, Buhlmann, Molnar, Ostermann, Kielstein, Wendel-Garcia, Bode, Stahl

#2106Genetics & Molecular BiologyFront Page28 November 2025

Synthetic Biology Breakthrough: Building a Virus to Save Pigs

Researchers have successfully assembled a functional Pseudorabies virus genome using yeast-based recombination and CRISPR technology. This new platform overcomes the difficulties of editing complex viral DNA, paving the way for faster development of vaccines for the swine industry.

By Hu, Ke, Xiao, Shang, Yin, Li, Li, Hu, Qian, Wang

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