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Results for "Genetics & Molecular Biology"

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#191Environmental ScienceFront Page2 December 2025

Ballast Bedfellows: Unpicking the Ecology of Bacterial Stowaways

New research dissects the microbial communities lurking in ship ballast sediments, distinguishing between hardy generalists and complex specialists. The study reveals that while generalists are better adapted to toxic environments like heavy metals, it is the specialists that underpin the biodiversity of these artificial ecosystems.

By Lv, Mei, Kan, Han, Jiang, Cui, Shi

#192Genetics & Molecular BiologyFront Page16 November 2025

Genetic Screening Reveals Hidden Drivers of Severe Early-Onset Obesity

A comprehensive six-year study of over 1,000 individuals has highlighted the critical role of genetic screening in treating severe obesity. By analysing a panel of 22 genes, researchers successfully identified pathogenic variants in roughly 3% of cases, paving the way for more personalised medical interventions.

By Rama, Blond, Janin, Di‐Filippo, Cuerq, Marmontel, Rollat‐Farnier, Dieterlen, Segrestin, Nicolino, Disse, Perge, Collin‐Chavagnac

#193Genetics & Molecular BiologyFront Page25 November 2025

Expanding the Genome Editing Toolbox: Cas12a Unlocks New Areas of Yeast DNA

Standard CRISPR/Cas9 editing is limited by its preference for specific DNA markers, leaving parts of the yeast genome inaccessible. A new study introduces an optimised CRISPR/Cas12a system that targets thymine-rich areas, allowing scientists to edit previously unreachable genetic sequences with high precision.

By Xie, Cai, Bao

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