Global Intelligence Database
Scientists have upgraded a gene-silencing tool to make it far more precise. By embedding new components into the cellular machinery, they can effectively turn down the volume of specific genes, which could help researchers better understand diseases like ALS.
By Fu, Zhang, Zhou, Zheng, Sun, Zhuang, Bao, Gao
Using the SWOT satellite, researchers captured high-resolution, two-dimensional data of tsunami waves immediately following an 8.8 magnitude earthquake. This spaceborne approach overcomes the limitations of land-based sensors, offering a new way to pinpoint tsunami origins and improve future early warning systems.
By Sepúlveda, Nilsson, Yu, Carvajal, Brandin, Gabriel, Sandwell
Scientists have developed an artificial intelligence model to decipher why individuals respond differently to stimuli like exercise. This 'graph neural network', trained on thousands of skeletal muscle studies, can infer the unique molecular pathways within each subject, offering a new way to visualise personalised biology from standard laboratory data.
By Kawano
Researchers used zebrafish to investigate microexons, tiny gene fragments regulated by Srrm3 and Srrm4, finding that while individual deletions are often harmless, losing the regulators causes severe deficits. This suggests that major neurological issues arise from the combined effect of multiple minor disruptions rather than a single failure.
By Lopez-Blanch, Rodríguez-Marin, Mantica, Iñiguez, Permanyer, Kita, Mackensen, Codina-Tobias, Romero-Ferrero, Fernandez-Albert, Cuadrado, Bustelo, de Polavieja, Irimia