
#1691NeuroscienceFront Page2 December 2025
The Spinal Switch: How RIN1 Rewires Pain Signalling
A protein named RIN1 controls the molecular composition of spinal synapses, normally aiding development. However, nerve injury causes RIN1 levels to surge in adults, altering receptor structures and potentially rendering specific painkillers ineffective.
By Bai, Zhang, Wu, Gao, Li, Bai, Yang, Liu, Dang, Yang, Suo, Hu
