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#1591Medicine & HealthFront Page15 November 2025

The Brain's Unsung Heroes: How Lifestyle Remodels Your Astrocytes

Your daily habits, from exercise to sleep, physically remodel your brain's most abundant support cells, the astrocytes. This neural plasticity is a key mechanism by which a healthy lifestyle can improve cognition and potentially mitigate decline associated with ageing and neurological conditions.

By Augusto-Oliveira, Arrifano, Leal-Nazaré, Soares-Silva, Lopes-Araujo, Santos-Sacramento, Crespo-Lopez

#1592Medicine & HealthFront Page15 November 2025

How a Common Anaesthetic Poses a Hidden Risk After Gestational Diabetes

A common anaesthetic may pose a heightened risk to the developing brains of offspring from diabetic pregnancies. A new mouse study suggests that gestational diabetes primes the brain's immune cells, amplifying nerve cell damage and synaptic loss when exposed to the drug sevoflurane.

By Sun, Guo, Wu, Tao, Lin, Song, Zheng, Ma, Shen, Zhou, Xu

#1593Genetics & Molecular BiologyFront Page21 November 2025

Spider Peptides Exploit Cholesterol Levels to Target Melanoma

Researchers have identified that gomesins, peptides derived from spiders, selectively destroy melanoma cells by targeting specific membrane lipids. By exploiting the naturally lower cholesterol levels in these cancer cells, the peptides disrupt the cell membrane and inhibit vital pathways, offering a promising avenue for new treatments.

By Fernandez-Carrasco, Moral-Sanz, Kurdyukov, Monne, Hartmann, Magalhães Novais, Waller, McKinnon, Chung, Salazar Castejón, Rainho, Dekan, Kremsmayr, Jandl, Filipič, Pamplona, Jové, Fernandez-Rojo, Anderluh, Muttenthaler, Alewood, Procházka, Neely, Deplazes, Ikonomopoulou

#1594Computer Science & AIFront Page26 November 2025

Deep Learning Outperforms Standard Statistics in Brain Tumour Prognosis

Researchers have demonstrated that a deep learning model called DeepSurv predicts survival rates for adult-type diffuse glioma more accurately than traditional statistical methods. By effectively handling complex and incomplete clinical data, this neural network offers a robust tool for assessing patient outcomes.

By Li, Zhao, Xia, Zhang, Zhang, Miao, Xie, Yan, Zhou, Xin

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