
#1571Genetics & Molecular BiologyFront Page7 March 2026
The Silent DNA Surgeons: Catching Cellular Repair in the Act with a New CRISPR-Cas12a Biosensor
Scientists have developed a highly sensitive CRISPR-based sensor that detects DNA repair as it happens. By using a custom DNA 'trapdoor', the system directly translates a single repair event into a massive, readable signal without relying on clunky secondary reactions.
By Dong, Hu, Wang, Zheng, Cheng, Shu, Liu, Xin, Huang, Qian, Xiao, Fu, Wang