
#1511Medicine & HealthFront Page12 January 2026
The Silent Saboteur: Tracing the Genetic Glitch Behind Neutrophil Dysfunction in SLE
Researchers have identified a defect in the 'minor spliceosome' as a key driver of immune cell failure in lupus. This genetic processing error prevents neutrophils from building essential defence proteins, offering a new explanation for the disease's chronic inflammation.
By Blanco, Regmi, Carmona‐Rivera, Liu, Wang, Carlucci, Jackson, Manna, Hasni, Hafner, Sun, Kaplan