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#1421Genetics & Molecular BiologyFront Page23 December 2025

Unlocking Telomere maintenance mechanisms: A Pan-Cancer Proteomic Atlas

Researchers profiled 976 cancer cell lines to map the proteins driving replicative immortality. The study challenges the binary view of telomere elongation and identifies specific vulnerabilities for targeted drug development.

By Wu, Cai, Cross, Noble, Prest, Littleboy, Cohen, Edlundh, Koh, Xu, Noor, Bastami, Valentini, Richardson, Barthorpe, Arymanesh, Robinson, Hains, Garnett, Zhong, Reddel, MacKenzie

#1422Physics & AstronomyFront Page3 January 2026

Integrated Quantum Photonics: When Light Learns to Follow Orders

Researchers have successfully integrated photon pair sources and programmable interferometers onto a single Lithium Niobate-on-Insulator chip. This monolithic approach achieves high-fidelity entanglement, offering a scalable path for future quantum technologies.

By Maeder, Chapman, Sabatti, Finco, Kellner, Grange

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