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#1341Chemistry & Material ScienceFront Page10 November 2025

Copper Oxide Unlocks Cryogenic Carbon Monoxide Oxidation

Researchers have discovered that the earth-abundant cuprous oxide (Cu₂O) can oxidize carbon monoxide (CO) into carbon dioxide (CO₂) at temperatures below 100 K. This finding provides a rare example of an earth-abundant metal oxide performing at cryogenic conditions, offering significant advancements for sustainable chemistry and catalysis.

By Karagoz, Hu, Stenlid, Hu, Soldemo, Abild‐Pedersen, Marks, Öström, Stacchiola, Weissenrieder, Head

#1342Genetics & Molecular BiologyFront Page22 December 2025

Metabolic dysfunction-associated steatohepatitis: Chronic Stress Primes Liver for Cancer

Chronic stress forces hepatocytes to trade mature function for survival, activating cancer-associated programmes long before tumours appear. This mechanism links early cellular adaptation directly to future malignancy.

By Tzouanas, Shay, Sherman, Rubin, Mead, Dao, Tao, Lehrich, Eng, Patterson-Fortin, Butzlaff, Mana, Kolb, Walesky, Pepe-Mooney, Smith, Prakadan, Ramseier, Tong, Joung, Chi, McMahon-Skates, Winston, Jeong, Aney, Chen, Nissim, Zhang, Deshpande, Monga, Lauer, Goessling, Yilmaz, Shalek

#1343NeuroscienceFront Page27 November 2025

Brain Scans Reveal How Depression Amplifies Pain After Shoulder Surgery

Researchers have discovered that the dorsal anterior cingulate cortex acts as a neural bridge connecting preoperative depression to the severity of postoperative pain in rotator cuff patients. By combining brain imaging with machine learning, the study predicted pain outcomes with impressive accuracy.

By Chu, Wang, Wang, Zhao, Liu, Guo, Kang

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