Global Intelligence Database
Researchers discovered that exposing middle-aged mice to light and sound at a specific frequency reignited the production of new neurons. The study identifies TrkB signalling as the mechanism allowing these new cells to mature and integrate into the brain's circuitry.
By Trinchero, Herrero, Mugnaini, Soldi, Aguilar-Arredondo, Benas, Satorre, Kropff, Schinder
The enzyme CD38 accumulates in the brain's filtration system with age, depleting vital energy resources. A new drug, NTX-748, blocks this enzyme to restore metabolic function and reverse memory loss in mice.
By Verdin, Fang, Riley, Schneider, Perrone, Kumaar, King, Kauwe, Roberts, Hormazabal, Zhang, Millard, Liu, Jara, Aguirre, Baker, Murad, Ambrose, Tran, Martin, Zhang, Sellegounder, Melov, Furman, Tracy, Gerencser, Schilling, Ellerby
A meta-analysis of 742 children confirms that Eslicarbazepine acetate significantly reduces focal seizures compared to a placebo. However, the drug is linked to higher rates of specific adverse effects, such as drowsiness and double vision, necessitating careful clinical monitoring.
By Das, Haq, Anwar, Das, Asif, Naeem, Khan, Arshad, Javed, Akilimali