
#1161Medicine & HealthFront Page11 November 2025
Overcoming Drug Resistance in Lung Cancer: New Strategies Emerge
Resistance to EGFR tyrosine kinase inhibitors (TKIs) is a major challenge in treating EGFR-mutant non-small cell lung cancer (NSCLC). This review explores molecular mechanisms of resistance and highlights innovative treatment approaches, including combination therapies and molecular monitoring. The goal is to improve patient outcomes through a deeper understanding and proactive management of resistance.
By Zhao, Xu, Zhou, Zhang, Zhou, Miao, Yu, Zhang, Fan, Zhou, Li, Mok, Le, Li, Xia