Results for "Medicine & Health"

How a Keto Metabolite Could Supercharge CAR T cell therapy

Researchers have found that a specific molecule produced during a ketogenic diet significantly improves the energy and effectiveness of engineered immune cells in preclinical models. While human clinical trials are still required, this metabolic intervention suggests a relatively simple dietary strategy could make existing cancer treatments work harder.

By Liu, Guruprasad, Ramasubramanian, Madhu, Paruzzo, Han, Kelly, Shestov, Xu, Carturan, Zhou, Amses, Afriat, Litichevskiy, Lin, Dubowitz, Tangal, Zhang, McSween, Tan, Stella, Lee, Nason, Hua, Schneider, Sleeman, Zhang, Gabrielli, Yang, Pajarillo, Patel, Ghilardi, Patel, Joshi, Jiang, Jiang, Porazzi, Tchou, Keith, Li, Chong, Schuster, Milone, Rabinowitz, O’Connor, Thaiss, Levy, Ruella