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Results for "Genetics & Molecular Biology"

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#101Medicine & HealthFront Page14 November 2025

Beyond the Spark: Atrial Fibrillation Remodels the Heart's Engine

A new study in horses reveals that persistent atrial fibrillation, a common heart rhythm disorder, is not just an electrical problem. Researchers found the condition causes significant structural and metabolic remodelling in the heart's atrial chambers, with surprisingly few changes to the ion channels that govern electrical signals. This suggests that tackling these underlying physical changes, rather than solely the electrical disturbance, could be key to more effective treatments.

By Haugaard, Nissen, Schneider, Birk, Carstensen, Hopster‐Iversen, Altıntaş, Barrès, Kjøbsted, Wojtaszewski, Herum, Jespersen, Buhl

#102Genetics & Molecular BiologyFront Page17 November 2025

Decoding the Molecular Shift Behind Aggressive Brain Tumours

Researchers have identified specific molecular mechanisms that cause some recurring meningiomas to transform into malignant cancers while others remain low-grade. By analysing paired tumour samples, the study revealed that malignant transformation is driven by increased genetic mutations and distinct DNA methylation patterns that appear even before the disease recurs. These findings could pave the way for better prognostic tools to predict tumour aggression.

By Ohara, Miyawaki, Teranishi, Komura, Okano, Hongo, Dofuku, Ishigami, Sakai, Shimada, Katoh, Nagae, Ikemura, Ushiku, Morishita, Suzuki, Shin, Nakatomi, Ishikawa, Aburatani, Saito

#103Medicine & HealthFront Page12 December 2025

The Silent Erosion: Can Vitamins for Periodontitis Halt the Decay?

Periodontitis is a relentless inflammatory condition that destroys the bone supporting our teeth. A new review combines clinical data with network pharmacology to map how specific micronutrients might stop the body from attacking itself.

By Wang LR, Liu DX, Yu L, Gao L.

#104Chemistry & Material ScienceFront Page1 February 2026

Stepping Inside the Protein: The Future of Molecular Visualization

A new perspective paper argues that 2D screens are holding back chemical research, proposing a shift to immersive 'Molecular Holodecks' where scientists can physically manipulate atomic structures. This evolution from passive viewing to active, haptic interaction aims to align scientific tools with human spatial cognition.

By Mulholland, Abriata

#105Medicine & HealthFront Page12 February 2026

Sarcopenia: Why Molecular Precision May Succeed Where Pharmacology Has Failed

A comprehensive review details the shift from diagnosing muscle loss via physical function to identifying specific molecular drivers like mitochondrial dysfunction. While promising targets such as myostatin inhibitors exist, inconsistent trial designs continue to block clinical approval.

By Nguyen, Dao, Nguyen, Park, Jeong, Kim, Jo, Thieu, Zhao, Ding, Yu, Dung, Gariani, Kim, Ryu

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