#1061Chemistry & Material ScienceFront Page3 December 2025
Four for the Price of Two: Illuminating the Depths of Microscopy
Researchers have engineered a novel molecular strategy that marries two-photon absorption with negative photoswitching. This approach yields ultra-sharp, four-photon-like imaging resolution while minimising the tissue damage typically associated with deep-dive microscopy.
By Benitez-Martin, Rouillon, Fron, de Jong, Grøtli, Hofkens, Pischel, Andréasson
