Results for "General Science"

The Brain’s Unexpected Pruning Service: OPCs Join the Cleanup Crew

New research utilising human forebrain organoids reveals that oligodendrocyte progenitor cells (OPCs) play a crucial role in synaptic pruning. By employing the GAS6-AXL signalling pathway, these cells actively internalise synaptic material, suggesting a vital function in early human brain development beyond mere insulation.

By Gkogka, Malwade, Koskuvi, Ohtonen, Molnar, Bose, Ceccatelli, Koistinaho, Tiihonen, Schalling, Samudyata, Sellgren