Neuroscience21 November 2025

The Human Visual Cortex Follows a Universal Mathematical Code

Source PublicationPLOS Computational Biology

Primary AuthorsGauthaman, Ménard, Bonner

Visualisation for: The Human Visual Cortex Follows a Universal Mathematical Code
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How does the brain translate a bustling city street or a quiet forest into neural activity? New research suggests the answer lies in a complex, mathematical structure that had previously gone unnoticed. By analysing functional MRI (fMRI) responses to natural scenes, scientists found that the visual cortex employs a consistent "scale-free organisation".

This means the variance in neural activity follows a power-law distribution—a statistical relationship often found in nature where specific patterns persist across different scales—spanning four orders of magnitude. What makes this truly fascinating is its consistency. Using a method called hyperalignment to map neural responses between people, the team revealed that this high-dimensional spectrum is largely universal. Despite individual differences in brain anatomy, humans share a fundamental spectrum of visual information.

Traditional neuroscience has often focused on a small number of high-variance dimensions, essentially listening only to the loudest signals. However, these findings demonstrate that visual data is distributed systematically across the full dimensionality of cortical activity. To fully understand vision, we must move beyond simple models and examine this complex, shared architecture.

Cite this Article (Harvard Style)

Gauthaman, Ménard, Bonner (2025). 'The Human Visual Cortex Follows a Universal Mathematical Code'. PLOS Computational Biology. Available at: https://doi.org/10.1371/journal.pcbi.1013714

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