Medicine & Health14 January 2026
New Italian Obesity Treatment Guidelines: A Strategic Shift in Clinical Management
Source PublicationEating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity
Primary AuthorsBarazzoni, Buscemi, Busetto et al.

The Italian National Institute of Health has ratified new clinical standards defining obesity as a chronic, relapsing disease requiring multimodal intervention. These **obesity treatment guidelines** shift the focus from simple weight loss to risk stratification via abdominal fat distribution. The document serves as the new legal and clinical reference for Italian healthcare professionals.
The Limitations of Current Obesity Treatment Guidelines
Body Mass Index (BMI) is a blunt instrument. It fails to capture metabolic risk accurately. The expert panel identified a significant gap in how clinicians assess patient health based solely on height and weight. Relying exclusively on BMI ignores the metabolic havoc wreaked by visceral adiposity. The new mandate is clear: clinicians must adopt at least one anthropometric index of abdominal visceral fat distribution. This is not optional. It is a necessary step for accurate risk stratification. Without this data, treatment plans lack precision and fail to address the root causes of metabolic syndrome.Stratified Intervention Protocols
The response is a tiered approach. Medical Nutrition Therapy (MNT) is the foundational requirement for every patient. This is not merely a diet sheet. It requires a structured lifestyle intervention, preferably utilising a cognitive-behavioural therapeutic approach. Physical activity and dietary balance are non-negotiable components. The guidelines are explicit: MNT must be exhausted or deemed insufficient before escalation. If MNT does not achieve clinical targets, the protocol intensifies. Pharmacological agents become the preferred option for two specific groups: those with a BMI over 27 kg/m² with comorbidities, and those with a BMI between 30 and 39.9 kg/m², depending on individual goals. Surgery is reserved as the primary option for patients with a BMI exceeding 40 kg/m², or where other methods have failed to mitigate risk. This stratification prevents the premature use of invasive procedures while ensuring high-risk patients receive adequate care.Evidence-Based Structuring
The panel organised 13 specific clinical questions into four distinct domains: diagnostic criteria, medical nutrition therapy, medical/surgical interventions, and miscellaneous factors. This structure ensures no aspect of the disease is left to chance. By using the GRADE system, the Italian Society of Obesity (SIO) ensures these recommendations are not just expert opinion but are grounded in rigorous data analysis. This creates a legal reference point. It standardises care. It removes ambiguity from the clinical decision-making process.Outcomes and Quality of Life
Why does this matter? The data indicates that a weight reduction of at least 10% correlates with significant improvements. Patients report better quality of life. The risk of incident depression drops. This is the target. The guidelines provide the roadmap to hit it. By formalising these steps, the Italian health system moves away from ad-hoc advice toward a systematic, chronic disease management model. This protects patients from negligence and guides providers toward efficacy. The focus is no longer on vanity; it is on morbidity reduction.Cite this Article (Harvard Style)
Barazzoni et al. (2026). 'Italian clinical practice GRADE-based guidelines on the diagnosis and treatment of overweight and obesity, endorsed by the Italian National Institute of Health.'. Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity. Available at: https://doi.org/10.1007/s40519-026-01813-z