Chemistry & Material Science18 November 2025

Merging Biology and Engineering: The Rise of Living Materials

Source PublicationACS Applied Bio Materials

Primary AuthorsLi, Fornasiero, Xu et al.

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Nature is a master designer, yet even our best nature-inspired synthetic materials often lack the ability to adapt or repair themselves. A transformative solution has emerged in the form of 'living materials', which integrate living cells—such as bacteria, fungi, or algae—into abiotic (non-living) matrices.

By harnessing biological processes like biomineralisation (how organisms produce minerals) or programmable metabolism, these materials achieve a level of sustainability and responsiveness that traditional engineering cannot match. Researchers categorise these innovations into two distinct types: those where cells act as tiny factories to synthesise the material, and those where cells remain integrated as active components to provide specific functions.

The potential applications are vast, ranging from self-healing concrete and soft robotics to advanced solutions in energy and medicine. By combining advanced manufacturing with biological dynamism, these living materials are set to revolutionise how we approach health and sustainability.

Cite this Article (Harvard Style)

Li et al. (2025). 'Merging Biology and Engineering: The Rise of Living Materials'. ACS Applied Bio Materials. Available at: https://doi.org/10.1021/acsabm.5c01099

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living materialsbioengineeringsustainability