How Optically Addressable Spin Systems in Proteins Will Organise Future Biological Control
Source PublicationNature Biotechnology
Primary AuthorsMeng, Nie, Berger et al.

Optically addressable spin systems have been widely studied for quantum-sensing applications. In a recent laboratory study, researchers have demonstrated that specific natural flavoproteins can function as optically addressable spin systems controlled by radio waves.
These results were observed under controlled laboratory conditions, so real-world performance may differ.
Scaling Optically Addressable Spin Systems in Biology
The study measured how photogenerated spin-correlated radical pairs in cryptochrome and improved light-oxygen-voltage proteins respond to radiofrequency pulses. By applying magnetic field gradients, the team successfully modulated the proteins' photoluminescence. This direct measurement confirms that these biological molecules can host spin systems accessible via light and radio waves.
The Future of Bio-Quantum Tech
This discovery suggests that we can eventually organise quantum sensing directly within biological frameworks. As the field develops, this platform could change how we monitor and control biological processes. Anticipated developments include:
- Magnetic Field Sensing: Utilising natural proteins to detect and map magnetic fields at a molecular level.
- Spatial Modulation: Controlling protein photoluminescence precisely using magnetic gradients.
- Biological Control: Steering specific protein-mediated biological processes using non-invasive radiofrequency signals.
By merging quantum physics with biology, this research centres on a future where biological systems can be monitored and steered with quantum precision.