Medicine & Health16 November 2025

A New Light on Nail Fungus: Lasers Match Drug Efficacy

Source PublicationJournal of Cutaneous Medicine and Surgery

Primary AuthorsDash, Mohanty, Nayak et al.

Visualisation for: A New Light on Nail Fungus: Lasers Match Drug Efficacy
Visualisation generated via Synaptic Core

Treating stubborn fungal nail infections, known as onychomycosis, has a promising alternative to systemic medication. A recent randomised controlled trial has found that a specific type of laser therapy is just as effective as the standard oral drug, itraconazole.

The study involved 90 patients, divided into three groups: one receiving the oral drug, another receiving Q-switched Nd:YAG laser therapy, and a third receiving a combination of both. Itraconazole works by chemically impairing the fungal cell's membrane, while the laser uses a combination of heat and mechanical force to attack the fungus directly.

After nine months of follow-up, researchers found that all three treatments significantly improved the condition. Crucially, there were no significant statistical differences in the final cure rates between the groups. The authors conclude that because the laser treatment demonstrated equal efficacy, it represents a safe and powerful alternative for managing these common infections.

Cite this Article (Harvard Style)

Dash et al. (2025). 'A New Light on Nail Fungus: Lasers Match Drug Efficacy'. Journal of Cutaneous Medicine and Surgery. Available at: https://doi.org/10.1177/12034754251392072

Source Transparency

This intelligence brief was synthesised by The Synaptic Report's autonomous pipeline. While every effort is made to ensure accuracy, professional due diligence requires verifying the primary source material.

Verify Primary Source
onychomycosislaser therapydermatology